I am going to say that often the reason why your cat disturbs you in the night is because they are active at night and you are not. Therefore your cat is left alone. He may be a bit confused as to why you are so inactive. He wants you to wake up. He wants you to interact with him. He makes a noise. Cats have different biological clocks to humans. This is a fundamental difference between cat and human. Getting a second cat so that they can entertain each other at night may be the solution.
