Advantage® II for cats contains an active ingredient which acts on the nervous system of the flea. It is called: midacloprid, an insecticide. It is interesting to me that it attacks the flea’s nervous system.
This chimes with at least two comments that I have noticed on this product. One is on this website and the other on Amazon. Here are the comments:
The first couple of days after applying this product to my cats it seemed to be working great. Especially for my cat who seems to be very sensitive to fleas. However today I watched one of them fall off a fairly tall piece of furniture twice (something he is on every day and has never fallen off of before) and strangely like he went limp or something. Then a little while later I watched as my other cat who was just standing on the floor fell with her back legs slamming together and her front paws trying to get a grip. Then I read on a few different websites that it has been found that in RARE occasions this product can have neurological effects….(Amazon).
My 4 year old cat cocoa is an indoor cat but she gets out sometimes i recently changed her liter to all natural liter and gave her a dose of small cat advantage 2 which was dose number two of three but instead of every month i give her every couple months never noticed her being allergic to it but after letting her inside one day the day after i noticed she was hiding out on top of a bin i lifted her up and she waslimp for the next couple of days she wouldnt eat or get up when she did it took a lot of energy i noticed a line of fur missing no wound and nowher belly near her nipples is reddish brown i have an appt in a couple days but it is killing me not knowning please help…(this website).
Each cat caretaker needs to check this out themselves but it appears that the insecticide can also attack the nervous system of the cat. The vetinfo.com website states in reference to its use on dogs:
It can enter his circulatory system and cause brain damage and nerve damage.
That statement supports the comments of the two users quoted on this page. Although, the website states it is one of the safest treatments for fleas on dogs.
Now, as far as I am concerned if a potential, albeit rare, side effect is this serious, it is unusable. It is about risk but it is also about the upside and downside of using drugs like these and insecticides are dangerous chemicals.
The vetinfo website adds an important extra bit of information about this drug. They say some of the inert ingredients in the product are not tested for safety because they don’t have to be under the law. Also, even if these inert ingredients are toxic they don’t have to list them. I’ll quote the site verbatim for the punch line:
Such undisclosed ingredients might be unsafe for use on your pet and the neurological damage caused by them may be permanent.
Has anyone more knowledge about this flea treatment? When I see “neurological damage” and “permanent” in one sentence as a possible side effect it puts me off buying it. Does it do the same thing to you?